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KMID : 1377020150120030143
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Tissue Engineering and Regenerative Medicine
2015 Volume.12 No. 3 p.143 ~ p.153
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Bioactive injectables based on calcium phosphates for hard tissues: A recent update
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Roman A. Perez
Shin Song-Hee
Han Cheol-Min
Kim Hae-Won
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Abstract
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Self-gelling/setting injectable biomaterials hold great promise for the delivery of bioactive molecules and cells useful for tissue engineering and regenerative medicine. In the biopolymeric regime, a broad compositional spectrum has been developed, yet very limited compositional options have been developed for inorganic injectables. For example, calcium phosphate (CaP)-based injectables are considered to be one of the most promising classes of materials for bone repair and reconstruction. Here we present an update on the recent advancements in CaP-injectables, where significant efforts have been undertaken to improve the regenerative capacity by tailoring the chemical compositions and increasing the drug delivery potential.
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KEYWORD
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Calcium phosphates, Injectables, Bone tissue engineering, Regenerative capacity, Drug delivery
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